A conjunctival nevus is a pigmented lesion that occurs in the conjunctiva, a thin, clear layer covering the white part of the eye and the cornea. It usually appears in brown, yellow or pink tones and can be present from birth or develop during adolescence or young adulthood.

Nevus are mostly benign formations and do not usually require treatment unless there is growth or discoloration. However, regular follow-up is important as it may carry the risk of malignant transformation in very rare cases.

What are the Symptoms and Clinical Features of Conjunctival Nevus?

Conjunctival nevus usually does not cause any obvious symptoms. However, in some cases the following symptoms may be observed:

  • It causes visible cosmetic discomfort on the surface of the eye.
  • Flat, brown or black lesions on the white of the eye
  • The lesions are usually painless and do not affect vision. Very rarely,
  • It may cause slight irritation in the eyes.
  • If the pigmentation has width, density or irregular edges, the risk of malignancy should be considered.
  • Primary Acquired Melanosis usually occurs in middle-aged individuals and may be associated with skin melanomas.

What are the Types of Conjunctival Nevus?

  • Primary Conjunctival Melanosis

It may be congenital or genetic. It is usually seen symmetrically and in more than one focus. The risk of malignant transformation is low.

  • Primary Acquired Conjunctival Melanosis (PAM)

It occurs in adults. It is characterized by uneven, dark pigmentation. Malignant melanoma; There is a risk of development, especially if it is accompanied by atypical cells.

  • Congenital Melanosis Oculi

It is the increase in pigmentation present from birth. It is usually unilateral and has a nevus-like appearance.

  • Nevus

It is a benign structure and the risk of malignancy is low. It usually remains stable, but change in color or size should be monitored for risk of malignancy.

  • Secondary Conjunctival Melanosis

It may develop due to chronic inflammation, trauma, drug use or a systemic disease.

How is Conjunctival Nevus Diagnosed?

Diagnosis of conjunctival nevus is usually made during an eye examination. An experienced ophthalmologist can make a diagnosis by examining the size, shape, color and location of the nevus. If necessary, advanced imaging techniques such as ultrasound biomicroscopy or optical coherence tomography (OCT) can be used to evaluate the risk of malignancy.

During the clinical examination, the extent and appearance of pigmentation on the eye surface is evaluated. The depth and spread of the lesions are examined with biomicroscopy (Slit-Lamp). Biopsy is also performed if there is an atypical appearance or suspicion of malignancy. Histopathological examination is also important to determine the risk of cellular atypia and malignant melanoma.

What are the Treatment Methods for Conjunctival Nevus?

Most conjunctival nevi do not require treatment. However, in the following cases, treatment may vary depending on the type and size of the lesion and the risk of malignancy.

  • Conjunctival Nevus Follow-up

For benign nevus or primary melanosis, regular follow-up alone may be sufficient if there are no significant changes.

  • Cosmetic Reasons for Conjunctival Nevus Treatment

The patient may prefer to have the nevus removed due to aesthetic concerns.

  • Suspicion of Malignancy in Conjunctival Nevus Treatment

When features such as rapid growth, irregular borders or color change are observed in the nevus; If there is a diagnosis of malignant melanoma, biopsy, surgical excision, cryotherapy or radiotherapy may be required. Biopsy and excision is recommended for suspicious or rapidly growing lesions. Ocular surface reconstruction may be required after excision for eye protection.  Cryotherapy or laser may be used to treat some pigmented lesions.

  • Causes of Complications in Conjunctival Nevus Treatment

Rarely, nevus may cause eye irritation or other symptoms.

A surgical operation in the treatment of conjunctival nevus is usually performed under local anesthesia and is a very safe procedure. After surgery, the nevus is completely removed and pathological examination is performed.

Why is regular follow-up important for conjunctival nevus?

Although the chances of a conjunctival nevus developing into a serious condition such as malignant melanoma are very low, it cannot be completely ruled out. When pigmented lesions are noticed, it is necessary to consult an ophthalmologist to exclude malignancy.

Although eye moles are generally benign, lesions with a risk of progression should be monitored. Therefore, the condition of the nevus should be monitored by having a regular eye examination once a year.

Op. Dr. Reliable Treatment with Ömer TAKEŞ

In our clinic located in Izmir Alsancak, we use the most advanced technologies in the diagnosis and treatment of conjunctival nevus and other eye diseases. Op. Dr. Ömer TAKEŞ offers a personalized and professional service to his patients with his experience in his field of expertise.

If you notice any spots or abnormal appearance in your eyes, you can visit our clinic for a detailed evaluation.

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